2) Shortening my cadence (especially when going up or down). 3). Working on my foot strike, making sure I'm not staying just on my toes when running flat parts, and making sure I'm not staying flexed back all the time when running uphill. 4) losing weight. 5) Increasing my volume in training, while listening to my body. Anytime I feel something starting up in my calves, I will shift my workouts to intervals so my calves have a chance to rest. If I overwork my calves, it takes them a week to recover. 6) stretching more often, 7) electrolytes on long runs.
If I had to order them, I'd go 1) supershoe, 2) losing weight, 3) cadence (which seems to fix my foot strike issues). 4) listening to body, 5) electrolytes, 6) foot strike, 7) stretching
Calves are also my limiting factor, but I've gone from slow and unable to run more than a couple miles to running a 39 minute 10k in just a few years (you're probably faster than me, but I'm thrilled with my progress). I'm 41 and my endurance running is as good as I could have ever hoped.