Besides that, the U.S. has shown they can bounce back from a loss and get a result against even good teams. Getting at least a draw against Uruguay with their backs against the wall should almost expected.

Even if they lost 2-0 to Uruguay, Panama would need a three-goal win over Bolivia to pass us in goal difference. A 2-0 win would only make them even on goal difference, and I assume the next tiebreaker is goals scored. In matching 2-0 results, Panama would advance. But if the U.S. lost 3-1 or 4-2 against Uruguay, then they’d advance over Panama.

If Panama beats the U.S. tonight, then I think it’s fair to say that Panama has the edge, but still maybe not the drivers seat. Depending on the scoreline, the U.S. might still have the edge over Panama in all the tiebreakers going into the last match.