Then you transfer there.

I often use point.me to find the best deal. Say you want to fly to Hawaii. Look at all transfer partners for the best deal, being flexible with dates helps, then transfer there

Eg. We redeemed round trip Hawaii for 25k (forgot which airline) and transferred another batch to KLM/Air France for Paris/amsterdam RT for 30-45k

You’re best to let them sit in Amex until decided when, how, and where to use them