I would play Chase, JoJo, Lassiter, and Marion all at the same time. Run lots of deep routes putting strain on the other team's safeties. I would utilize Jake as the primary run threat if they can't keep enough people in the box. Additionally, TE's are used as extra protection as needed but are used as leak outs to the flat, drag routes etc. All plays are going to the WRs and TEs and as the D eventually softens the box, you use Jake's legs.
When LJ comes back we can reassess.