I'm playing with the lead against two opponents who have McCaffrey in their lineup.
In one of the leagues, I'm up by 40 points so it probably wouldn't matter anyway.

In the other, I'm up by a meager 18.5 points. It's a PPR league.
His QB is Lamar Jackson.

I look at his bench and I see Tua Tagovailoa.... seriously.
Instead of grabbing Jordan Mason, he took a second QB while there are playable, unowned QBs like Jared Goff. Goff doesn't run, so I wouldn't want him as my QB, but neither does Tagovailoa.

It's a shame that it's too late for trades to process before the game starts. Jordan Mason is on my bench just waiting for a McCaffrey injury. I'd have made a trade with him if he were willing to sacrifice something big.