I like super low risk things for most (almost all) of my investing. Dividend stocks, but I like the dividend ETFs (For example:
http://www.dividend.com/dividend-etfs/) for further diversification, and good (not at all great) yields.
For a very small portion of what I do, I like to do massively high-risk high reward stuff. For example, I like distressed stocks (especially where the "shadow" hanging over them is a legal issue-- I'm an attorney and feel pretty qualified to evaluate that stuff). They are almost always valued wrong. If they win their legal or other issue, they are generally going to get a massive bump. If they lose they are going to zero (or something like it). But the market values them in between. I view that as an opportunity to get a big upside for a very small price using options, basing it on what I think is going to happen.
I also do other non-traditional stuff like angel investing in local startups-- which is super fun if you know enough to do it well. Outwitting the public market consistently and trying to guess highs and lows and economic trends is not really for me. In general, I keep a diversified pool of things to grow slowly but which are unlikely to retreat much, and then I pick a few very specific spots to put my eggs in a particular basket that I can watch carefully, based on a lot of research and care. With that piece of the pie I try to set it up so that I can lose 5-6X and have one win and still double my money.