I think BYU wins that game, but last year's Wyoming team went 9-4. Yes, they have a new head coach and this year's team isn't that team, but they've been playing well. In fact, they haven't had a losing season since 2015 (2020 excluded).
If that game were in Provo, I think BYU handles the Cowboys no problem, but in Laramie? That's a lose-able game. I think BYU wins, but it's not a guaranteed win.