Out as fast as you can and burn up all your energy before the snap. Then you need to make a rule that the O can’t sub anymore.
If the offense pulls a TE and replaces him with a fast WR, defense should get a chance to pull their LB and put a corner on him to keep up with his speed.
I’d be ticked if I was the DC and wasn’t given time to sub in a different player if the O switched someone out.