Quite the contrast in that state.
I-80 some of my least favorite territory in the US of A (although Cheyenne isn’t terrible)
Then you have Star Valley, Jackson, Grand Targhee, The Tetons, Yellowstone, The Big Horns, etc. Some of my favorite places are in that list.
But I-80—never a pleasure, can be impassible or downright treacherous in winter. One stop for food/gas or perhaps at Little America, but otherwise, best to get it over with and get out.