the games go to chalk with no upsets. In 2021 BYU a 4 seed beat the 1 seed Virginia in the sweet 16 at Virginia.

Then the regional finals (national quarterfinals) goes back to a single game at the highest remaining seed.

In 2021 after BYU beat Virginia, BYU as a 4 seed hosted the quarterfinal match against unseeded South Carolina. South Carolina upset 2 seed North Carolina in the first round and then USC who hosted the sweet 16 quadrant as the 3 seed (taking the hosting chance of North Carolina who was knocked out already) got knocked out in the round of 32 game.