missing 4 games to a shoulder injury.

In a 2022 game, he recorded five total touchdowns against Houston and 100 yards rushing and won multiple player of the week awards: Walter Camp Offensive Player of the Week, the Big 12 Offensive Player of the Week, and Manning Award Star of the Week. Kansas also received votes to be ranked for the first time since 2009. In the Jayhawks' 55–53 loss to Arkansas in the 2022 Liberty Bowl, Daniels set a program record for passing yards in a game with 544 yards. His performance was also a Liberty Bowl record.

He was selected as the 2023 Big 12 Preseason Player of the Year, the first Kansas player to receive the award. He was also selected as a preseason First Team All-Big 12 quarterback and to the watch lists for the Davey O'Brien Award, the Walter Camp Award, and the Manning Award before the season. He missed the Jayhawks' opening game of the season due to an injury. Returned for the Illinois game, was lost to the season due to an injury pre-game against Texas.

EPSN named him to a Heisman watch list before this season.