I have a bunch of S&W pistols I like a lot (M&P 40C, M&P 40 Shield, 45 Shield, and 9mm Shield), but I favor my Sigs just a little more.
My EDC is the Sig P365, it's really small but still fits my hand great, and you can't beat the capacity with its 12 round mag. I also like shooting the P938 and of course the P320. I have some .380s my wife like to shoot also.
Of all my pistols, I shoot best with the 365 and the 40 Shield. Glock is a great brand but I just don't enjoy shooting any of them, plus every semi auto pistol I have has a safety. No safety with Glock.
I think the best thing to do is go shoot with a friend who has a lot of different pistols and see what you're most comfortable shooting. If you're looking to carry that will steer you in a different direction as well.