Using a mix of PFF grades and Mel Kiper's big board, here are the top options at each position. I know this doesn't necessarily equate to "best players" but whatever:
QB: Trevor Lawrence (Mac Jones and Zach Wilson are the other two top options. Justin Fields could obviously go here as well.)
RB: Travis Etienne is the star. Highest rated on PFF is Javonte Williams (UNC)
WR: DeVonta Smith
WR: Jaylen Waddle
WR: Dax Milne (no joke he's PFF's #3). But you could also put Rashod Bateman (Minnesota) or Elijah Moore (Ole Miss) here of course.
TE: Kyle Pitts (FLA)
OT: Brady Christensen (PFF's #1 tackle by quite a bit)
OT: Penie Sewell
OG: Wyatt Davis (tOSU)
OG: Trey Smith (Tennessee)
C: Noah Hannon (App St)
That team would dominate the college game. They'd lose by 4 TDs or more to the Jets.