1. Get pressure on QB. Regardless of whether Wilson or Rose, if BYU can get consistent pressure on the QB, BYU wins. They are both inexperienced QBs who are prone to make mistakes under pressure. From the beginning of the game the defense needs to make a statement by getting pressure on the QB.
2. Don't turn the ball over. If BYU gets pressure on the QB and doesn't turn the ball over, they win.